Sr. Biologist - Immunology Discovery

Location: San Diego
Posted on: June 23, 2025

Job Description:

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We’re looking for people who are determined to make life better for people around the world. We are seeking a motivated and collaborative Associate Scientist to join our Immunology Discovery team. This role plays a key part in the identification and validation of novel therapeutic targets by integrating cellular assays, molecular techniques, and immunological insights to support early discovery efforts. The successful candidate will contribute to the development of therapeutics for autoimmune and inflammatory diseases by designing and executing in vitro assays, analyzing data, and collaborating across multidisciplinary teams. Responsibilities: As a Sr. Biologist in Discovery Immunology, you will support the discovery and development of novel immunomodulatory therapies by developing cellular assays, executing in vitro experiments, and assessing functional changes in response to various perturbations. You will contribute to the early-stage validation of therapeutic targets and work closely with cross-functional teams to advance promising candidates toward clinical development. Develop and optimize cell-based assays using primary immune cells from various species, including human, non-human primate, and mouse. Assess immune cell function by utilizing techniques such as flow cytometry, MSD, ELISA, and qPCR. Design and execute experiments and analyze resulting data to evaluate novel molecules in cell-based assays. Communicate experimental data effectively through written reports and oral presentations. Collaborate effectively within cross-functional teams that include other biologists, bioinformaticians, and translational scientists to achieve project goals. Demonstrate flexibility and motivation to learn and apply new technologies for biological assays. Basic Requirements: Bachelor’s degree in Immunology, Cell Biology, or a related field plus 5 years of relevant experience in biotechnology, pharmaceutical industry, or academic research in the field of immunology. Master’s degree in Immunology, Cell Biology, or a related field plus 2 years of relevant experience in biotechnology, pharmaceutical industry, or academic research in the field of immunology. Additional Skills/Preferences: Proficient in developing in vitro assays, including work with human cell lines, PBMCs, and whole blood assays. Proficient in multi-color flow cytometry (?5-color panels; BD Fortessa or Cytek). Proven ability to utilize molecular biology techniques, including DNA/RNA isolation, qPCR, and Western blotting. Prior work with CRISPR/Cas9 gene editing techniques. Previous experience with single-cell multiomics technologies, such as CITE-seq or spatial transcriptomics. Familiar with in vivo disease models. Experience with 3D organoid culture and immunostaining. Strong data analysis skills using FlowJo, GraphPad Prism, and Excel. Strong analytical, problem-solving, and decision-making skills. Excellent interpersonal and communication skills. Ability to work independently and collaboratively within a team environment. Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response. Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status. Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ Allies), Veterans Leadership Network (VLN), Women’s Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups. Actual compensation will depend on a candidate’s education, experience, skills, and geographic location. The anticipated wage for this position is $69,000 - $179,300 Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly’s compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees. WeAreLilly

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